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We seen an increased expression away from osteopontin, cathepsin K and you can TG2 mRNA in the calcific areas of the new supraspinatus ligament versus what observed in the typical tissues 48. TG2 are ubiquitously shown, and you will plays a role in multiple cellular processes, for instance the crosstalk anywhere between macrophages and you can apoptotic muscle, sugar endurance or other techniques.